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- Record Of The Year – Rolling In Deep by Adele
- Album Of The Year – 21 by Adele
- Song Of The Year – Rolling In Deep by Adele
- Best New Artist – Bon Iver
- Best Pop Solo Performance – Someone Like You by Adele
- Best Pop Duo / Group Performance – Body and Soul by Tony Bennett and Amy Whinehouse
- Best Pop Instrumental Album – The Road From Memphis by Booker T. Jones
- Best Pop Vocal Album – 21 by Adele
- Best Dance Recording – Scary Monsters And Nice Sprites by Skrillex
- Best Dance / Electronica Album – Scary Monsters And Nice Sprites by Skrillex
- Best Traditional Pop Vocal Album – Duets II by Tony Bennett & Various Artists
- Best Rock Performance – Walk by Foo Fighters
- Best Hard Rock / Metal Performance – White Limo by Foo Fighters
- Best Rock Song – Walk by Foo Fighters
- Best Rock Album – Wasting Light by Foo Fighters
- Best Alternative Music Album – Bon Iver
- Best R&B Performance – Is This Love by Corinne Bailey Rae
- Best Traditional R&B Performance – Fool For You by Cee Lo Green & Melanie Fiona
- Best R&B Song – Fool For You by Cee Lo Green & Melanie Fiona
- Best R&B Album – F.A.M.E. by Chris Brown
- Best Rap Performance – Otis by Jay-Z, Kanye West
- Best Rap / Sung Collaboration – All Of The Lights by Kanye West, Rihanna, Fergie, & Kid Cudi
- Best Rap Song – All Of The Lights by Kanye West, Rihanna, Fergie, & Kid Cudi
- Best Rap Album – My Beautiful Dark Twisted Fantasy by Kanye West
- Best Country Solo Performance – Mean by Taylor Swift
- Best Country Duo/Group Performance – Barton Hallow by The Cival Wars
- Best Country Song – Mean by Taylor Swift
- Best Country Album – Own The Night by Lady Antebellum
- Best New Age Album – What’s It All About by Pat Metheny
- Best Improvised Jazz Solo – 500 Miles High by Chick Corea
- Best Jazz Vocal Album – The Mosaic Project by Terri Lyne Carrington & Various Artists
- Best Jazz Instrumental Album – Forever by Corea, Clarke & White
- Best Large Jazz Ensemble Album – The Good Feeling by Christian McBride Big Band
- Best Gospel / Contemporary Christian Music Performance – Jesus by Le’Andria Johnson
- Best Gospel Song – Hello Fear by Kirk Franklin
- Best Contemporary Christian Music – Blessings by Laura Story
- Best Gospel Album – Hello Fear by Kirk Franklin
- Best Contemporary Christian Album – And If Our God Is For Us… by Chris Tomlin
- Best Latin, Pop, Rock or Urban Album – Drama Y Luz by Maná
- Best Regional Mexican or Tejano Album – Bicentenario by Pepe Aguilar
- Best Banda or Norteno Album – Los Tigres Del Norte And Friends by Los Tigres Del Norte
- Best Tropical Latin Album – The Last Mambo by Cachao
- Best Americana Album – Ramble At The Ryman by Levon Helm
- Best Bluegrass Album – Paper Airplane by Alison Krauss & Union Station
- Best Blues Album – Revelator by Tedeschi Trucks Band
- Best Folk Album – Barton Hollow by The Civil Wars
- Best Regional Roots Music Album – Rebirth of New Orleans by Rebirth Brass Band
- Best Reggae Album – Revelation Pt 1: The Root Of Life by Stephen Marley
- Best World Music Album – Tassili by Tinariwen
- Best Children’s Album – All About Bullies… Big And Small by Jim Cravero, Gloria Domina, Kevin Mackie, Steve Pullara & Patrick Robinson
- Best Spoken Word Album – If You Ask Me (And Of Course You Won’t) by Betty White
- Best Comedy Album – Hilarious by Louis C.K.
- Best Musical Theater Album – The Book Of Mormon by
Josh Gad & Andrew Rannells, artists; Anne Garefino, Robert Lopez,
Stephen Oremus, Trey Parker, Scott Rudin & Matt Stone, producers; Robert Lopez, Trey Parker & Matt Stone
- Best Compilation Soundtrack for Visual Media – Boardwalk Empire: Volume 1 by Stewart Lerman, Randall Poster & Kevin Weaver
- Best Score Soundtrack For Visual Media – The King’s Speech by Alexandre Desplat
- Best Song Written for Visual Media – I See The Light (From Tangled) by Alan Menken & Glenn Slater
- Best Instrumental Composition – Life In Eleven by Béla Fleck & Howard Levy
- Best Instrumental Arrangement – Rhapsody In Blue by Gordon Goodwin
- Best Instrumental Arrangement Accompanying Vocalist(s) – Who Can I Turn To (When Nobody Needs Me) by Jorge Calandrelli
- Best Recording Package – Scenes From The Suburbs by Caroline Robert
- Best Boxed or Limited Edition Package – The Promise: The Darkness On The Edge Of Town Story by Dave Bett & Michelle Holme
- Best Album Notes – Hear Me Howling!: Blues, Ballads & Beyond As Recorded By The San Francisco Bay By Chris Strachwitz In The 1960s
- Best Historical Album – Band On The Run (Paul McCartney Archive Collection – Deluxe Edition) by Paul McCartney
- Best Engineered Album, Non-Classical – Paper Airplane by Neal Cappellino & Mike Shipley
- Producer of the Year, Non-Classical – Paul Epworth
- Best Remixed Recording, Non-Classical – Cinema (Skrillex Remix) by Skrillex
- Best Surround Sound Album – Layla And Other Assorted Love Songs (Super Deluxe Edition) by Elliot Scheiner
- Best Engineered Album, Classical – Aldridge: Elmer Gantry by Byeong-Joon Hwang & John Newton
- Producer of the Year, Classical – Judith Sherman
- Best Orchestral Performance – Brahms: Symphony No. 4 by Gustavo Dudamel
- Best Opera Recording – Adams: Doctor Atomic by Alan Gilbert
- Best Choral Performance – Light & Gold by Eric Whitacre
- Best Small Ensemble Performance – Mackey: Lonely Motel – Music From Slide by Rinde Eckert & Steven Mackey
- Best Classical Instrumental Solo – Schwantner: Concerto For Percussion & Orchestra by Giancarlo Guerrero
- Best Classical Vocal Solo – Diva Divo by Joyce DiDonato (Kazushi Ono; Orchestre De L’Opéra National De Lyon; Choeur De L’Opéra National De Lyon)
- Best Contemporary Classical Composition – Aldridge, Robert: Elmer Gantry by Robert Aldridge & Herschel Garfein
- Best Short Form Music Video – Rolling In The Deep by Adele
- Best Long Form Music Video – Foo Fighters: Back And Forth by Foo Fighters
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